Impact of substance use disorders on critical care management and health outcomes in septic adolescents.

ABSTRACT:

Background

Adult septic patients with substance abuse disorder (SUD) are at increased risk of poor outcomes, but the impact on adolescents is unknown. We aimed to determine if pre-existing SUD is associated with increased adverse outcomes and critical care resources in critically ill adolescents hospitalized with sepsis. We hypothesize that SUD is associated with increased risk of adverse outcomes and usage of critical care resources in this adolescent patient population.

Methods

This was a retrospective cohort study utilizing the TriNetX© electronic health record (EHR) database, which consists of EHR from participating healthcare organizations predominantly in the United States. Critically ill adolescents with sepsis aged 12-21 years were divided into two groups (SUD histor

SUBMITTER: Markus H 

PROVIDER: S-EPMC12065691 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature