Preoperative BOLD cerebrovascular reactivity correlates with intraoperative STA-MCA bypass flow and influences postoperative CVR improvement.

ABSTRACT:

Introduction

The superficial temporal artery-middle cerebral artery (STA-MCA) flow augmentation bypass is effective for treating Moyamoya vasculopathy and selected cases of atherosclerotic large vessel disease. Recently, blood oxygen level-dependent cerebrovascular reactivity (BOLD-CVR) has emerged as a novel tool to assess hemodynamic impairment for patient selection and monitoring. This study investigates whether preoperative BOLD-CVR in the affected vascular territory (i.e. middle cerebral artery (MCA) territory) correlates with intraoperative bypass flow and whether intraoperative bypass flow serves as a predictor of postoperative hemodynamic improvement.

Patients and methods

We prospectively included patients with symptomatic cerebrovascular steno-occlusive disease who

SUBMITTER: Sebok M 

PROVIDER: S-EPMC12065708 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature