Identification & genetic & virological characterisation of a human case of avian influenza A (H9N2) virus from Eastern India.

ABSTRACT: Background & objectives A three-year-old male child from West Bengal, India, with severe acute respiratory symptoms, was confirmed in the laboratory with LPAI H9N2 virus infection under the Indian Council of Medical Research (ICMR) - Pan India Acute Respiratory Infections (ARI) / Severe Acute Respiratory Infections (SARI) surveillance through the Virus Research and Diagnostic Laboratories network. Methods Common respiratory viruses were detected by real-time PCR, followed by subtyping of Influenza A for seasonal and avian viruses. The identified H9N2 virus was isolated and further characterised, including whole genome sequencing. Antibody response was performed in serum samples of the case and family members. Results Complete genome sequencing revealed a G1 lineage (Middle East B sub-linea

SUBMITTER: Majumdar A 

PROVIDER: S-EPMC12066128 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature