Vaccination with inactivated SARS-CoV-2 vaccine TURKOVAC induces durable humoral and cellular immune responses up to 8 months.

ABSTRACT:

Background

The rapid spread of the SARS-CoV-2 virus has led to a global health crisis, necessitating swift responses in medical science, mainly through vaccination strategies. While short-term vaccine effectiveness is evident, immune protection's long-term effects and duration remain incompletely understood. Systematic monitoring of these responses is essential for optimizing vaccination strategies.

Aims

This study aimed to explore the durability of antigen-specific T and B cell responses and antibody levels up to 8 months post-immunization with the inactivated TURKOVAC vaccine in volunteers. Additionally, the impact of two versus three doses of vaccination on these parameters was analyzed.

Methods

Volunteers (n = 80) received two or three doses of TURKOVAC. Sp

SUBMITTER: Yılmaz S 

PROVIDER: S-EPMC12066321 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature