Unveiling <i>Wolbachia</i> transcriptomic signature in the arboviral vector <i>Aedes aegypti</i>.

ABSTRACT:

Introduction

The mosquito Aedes aegypti is the main vector of arboviral diseases such as dengue and imposes a global health burden. A promising control strategy is to infect A. aegypti populations with Wolbachia, a genus of intracellular bacteria capable of blocking arboviral infections. Enhancing and preserving the efficacy of this method will depend on a solid mechanistic knowledge of the A. aegypti-Wolbachia symbiosis. By identifying differences between Wolbachia-infected and uninfected A. aegypti, previous transcriptomic studies proposed a wide range of symbiotic interactions, but a systematic identification of consistent effects across datasets is still missing.

Methods

To identify A. aegypti genes and functions consisten

SUBMITTER: Mejias S 

PROVIDER: S-EPMC12066770 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature