Estimating 24-hour urine phosphate excretion from spot urine.

ABSTRACT:

Background

24-hour urinary phosphate excretion (24hUrP) is indicative of intestinal phosphate absorption in steady-state conditions. Nevertheless, 24-hour urine collections are cumbersome and error-prone. Previous studies suggested that spot urine phosphate (uPi) could serve as a practical substitute to predict 24hUrP, however, these data originated only from patients with chronic kidney disease. Here, we investigated the validity of predictive equations using spot urine parameters to assess 24hUrP in a cohort with normal kidney function (eGFR >60 ml/min per 1.73 m²) including 761 kidney stone patients and 207 non-kidney stone formers as assessed by low-dose CT scans, the Swiss Kidney Stone Cohort (SKSC).

Methods

Published equations for 24hUrP were tested in our c

SUBMITTER: Li Y 

PROVIDER: S-EPMC12067064 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature