Stereoselective construction of coconformational mechanically helical and topologically chiral [2]catenanes induced by point chirality.

ABSTRACT: Supported by chiral stationary phase high-performance liquid chromatography HPLC (CSP-HPLC), examples of chiral mechanically interlocked organic molecules, including knots, rotaxanes, and catenanes, have been reported. However, the exploration of stereoselective construction of chiral cationic complexes, particularly those induced by point chirality, has been notably limited due to the constraints posed by the type of chiral chromatographic columns and separation efficiency. To address this, we have developed a construction strategy for generating coconformational mechanically helical and topologically chiral [2]catenanes through the induction of point chirality. In this study, by adjusting the symmetry of the ligand, we have easily realized the efficient construction of high-yield crystal

SUBMITTER: Tang H 

PROVIDER: S-EPMC12067221 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature