Nanomaterial Modified Screen Printed Electrode Based Electrochemical Genosensor for Efficient Detection of Neonatal Sepsis.

ABSTRACT: The present work reports fabrication of nanomaterial based electrochemical genosensor for efficient detection of neonatal sepsis. For this purpose, virulent cfb gene of its major causative organisms, i.e. Group B Streptococcus (GBS) was selected. Further, a cfb specific 19-mer long amine terminated DNA probe was designed to be used as bioreceptor. The genosensing platform is fabricated by utilizing graphene oxide as nanomaterial which is deposited onto screen printed electrode (SPE) by electrophoretic deposition technique. Thereafter, the designed probe DNA is immobilized on graphene oxide modified SPE through EDC-NHS chemistry. Characterization of nanomaterial and fabricated genosensing platform is studied via X-ray diffraction, Scanning electron microscopy, atomic fo

SUBMITTER: Gopal N 

PROVIDER: S-EPMC12069212 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature