Facility-measured nocturnal hypoxemia and sleep among adults with long COVID versus age- and sex-matched healthy adults: a preliminary observational study.

ABSTRACT:

Study objectives

Persistent post-acute sequelae of SARS-CoV-2 infection, i.e. long COVID, impacts multiple organ systems. While lower blood oxygen is expected when SARS-CoV-2 infects the lungs, hypoxia without pulmonary symptoms may continue after the acute phase. Ventilation and blood oxygen are more vulnerable during sleep, but nocturnal hypoxemia hasn't been studied in people with long COVID in a facility setting using gold-standard polysomnography (PSG).

Methods

We conducted an observational study with 50 participants (25 long COVID, 25 age-sex-matched healthy controls) using in-laboratory overnight PSG. We calculated the average SpO₂, average SpO₂ after removing desaturations, the respiratory rate in different sleep periods, and the hypoxic costs u

SUBMITTER: Sun H 

PROVIDER: S-EPMC12070477 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature