Bright light therapy in Parkinson's disease: a pilot study on visual pathway improvements.

ABSTRACT:

Background

Bright light therapy (BLT) has been proved to have beneficial effects on Parkinson's disease (PD), the mechanisms remained unclear. Improvements of visual pathways might be key to BLT.

Objective

The aim of this study is to validate whether BLT improves clinical symptoms in PD and explore the possible mechanisms of visual pathways evaluated by optical coherence tomography (OCT), pattern electroretinogram (PERG) and visual evoked potentials (VEP).

Methods

Twenty-three PD patients were enrolled in this crossover randomized placebo-controlled study. Participants received either one month of BLT or dim light therapy (DLT), separated by one-month wash-out period, followed by another intervention. Participants underwent clinical scales, and visual-related evaluati

SUBMITTER: Xie WY 

PROVIDER: S-EPMC12070497 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature