QUANTIFICATION OF CAPILLARY BLOOD FLOW SPEEDS IN DIABETIC RETINOPATHY USING VARIABLE INTERSCAN TIME ANALYSIS OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.

ABSTRACT:

Purpose

To investigate retinal capillary plexus capillary flow speed and vessel density in diabetic retinopathy and normal subjects using variable interscan time analysis optical coherence tomography angiography (OCTA).

Methods

High speed swept source OCTA imaging using multiple interscan times was performed over a 5 mm × 5 mm field-of-view with 600 kHz A-scan rate. Second-generation variable interscan time analysis OCTA was used to measure a surrogate marker for capillary blood flow speed, variable interscan time analysis flow speed (VFS), in the superficial and intermediate capillary plexuses VFS , and deep capillary plexus VFS . Vessel density was measured using OCTA.

Results

Fifty-seven eyes with different diabetic retinopathy severity and 37 normal eyes were anal

SUBMITTER: Hwang Y 

PROVIDER: S-EPMC12070804 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature