Expression Pattern of the AB1-Gal4 Driver in <i>Drosophila</i> Third-Instar Larvae.

ABSTRACT: Drosophila has provided a highly attractive model system for studying various tissue- and stage-specific processes as well as their pathologies, including a range of human diseases. The existence of a large number of diverse Gal4 drivers to precisely control the expression patterns of UAS transgenes simplifies such studies. However, the choice of driver is always critical, as its possible ectopic expression in non-target cells and tissues can directly impact the results. Therefore, it is very important to thoroughly characterize both the molecular nature and expression pattern of each Gal4 driver line. Here, we aim to fill such gaps regarding the AB1-Gal4 driver, which is typically used to express UAS transgenes in larval salivary glands. In this fly line, the P{GawB} enhancer trap

SUBMITTER: Ogienko AA 

PROVIDER: S-EPMC12071433 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature