Promising benefits of six-month <i>Phaeodactylum tricornutum</i> microalgae supplementation on cognitive function and inflammation in healthy older adults with age-associated memory impairment.

ABSTRACT:

Introduction

Aging is often associated with cognitive decline and memory impairment, with several factors including inflammatory cytokines and oxidative stress markers implicated in this natural process. Microalgae extracts are a natural source of many bioactive compounds that reduce inflammation and oxidative stress, and represent an innovative dietary approach to ameliorate age-related cognitive decline and memory impairment. This proof-of-concept CONSORT-compliant, double-blind, randomized controlled study was conducted to evaluate the effect of daily supplementation of microalgae extract on cognitive function, mood, stress and inflammation of healthy older adults with mild cognitive impairment over a 24-week period.

Methods

Sixty-six volunteers with age-associated memory

SUBMITTER: Goodbody E 

PROVIDER: S-EPMC12075122 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature