Consumption of only wild foods induces large scale, partially persistent alterations to the gut microbiome.

ABSTRACT: The gut microbiome (GM) is implicated in human health and varies among lifestyles. So-called "traditional" diets have been suggested to promote health-associated taxa. However, most studies focused only on diets including domesticated foods. Historically, humans consumed only wild foods, which might uniquely shape GM composition. We explored the impact of a wild-food-only diet on GM, particularly whether it increases the presence of health-associated and/or "old friend" taxa, and if the alterations to GM are persistent or transient. One participant collected daily fecal samples and recorded daily food consumption over an eight-week period, the middle four weeks of which he consumed only wild foods. Samples were profiled by 16S rRNA sequencing, and oligotyping and network analysis were cond

SUBMITTER: Rampelli S 

PROVIDER: S-EPMC12075472 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature