High intensity exercise programme in patients with hypertrophic cardiomyopathy: a randomized trial.

ABSTRACT:

Background and aims

The feasibility and impact of high intensity exercise programmes in patients with hypertrophic cardiomyopathy (HCM) are unknown. This study was conducted to determine the feasibility of a high intensity exercise programme and explore safety and efficacy outcomes in patients with HCM.

Methods

Participants were randomized to a 12-week supervised exercise programme (n = 40) in addition to usual care, or usual care alone (n = 40). All participants underwent assessment at baseline and 12 weeks. The exercise group was re-evaluated 6 months post-programme. Feasibility was assessed by (i) recruitment, adherence, and retention rates; (ii) staffing ratios; (iii) logistics; and (iv) acceptability of the intervention. The primary exploratory safety outcome was a comp

SUBMITTER: Basu J 

PROVIDER: S-EPMC12075935 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature