Aspirin does not modify cardiovascular event risk in endometriosis in the California Teachers Study.

ABSTRACT:

Aims

Endometriosis frequently affects reproductive aged females and is associated with increased cardiovascular disease risk. The aims of this study were (i) to confirm the relationship between cardiovascular disease and endometriosis and (ii) to test whether aspirin modified the effect of endometriosis on cardiovascular disease risk.

Methods and results

A longitudinal cohort study was conducted using data from the California Teachers Study from enrolment (1995-1996) through the current administrative end follow-up (31 December 2020). Primary outcome was any incident major adverse cardiovascular event (MACE) defined using validated ICD-9/ICD-10 codes for stroke, myocardial infarction, and coronary heart disease. Inverse probability (IP) weights were used to estimate the caus

SUBMITTER: Seitz A 

PROVIDER: S-EPMC12076410 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature