Characterization and purification of Pseudomonas aeruginosa phages for the treatment of canine infections.

ABSTRACT:

Background

Pseudomonas aeruginosa is an opportunistic pathogen that causes infections in both human and veterinary medicine, presenting significant challenges in treatment because of biofilm production and its intrinsic resistance. This problem is exacerbated by the increase in acquired antimicrobial resistance. Bacteriophage (phage) therapy has emerged as a promising alternative for treating infection classically treated with antibiotics, offering a targeted approach to combat this infection. This study aimed to evaluate the therapeutic potential of 7 phages, focusing on their suitability for treating canine infections, as well as their purification and safety analysis for therapeutic use.

Results

Two self-isolated phages and five provided phages were analysed. All tested p

SUBMITTER: Dalponte A 

PROVIDER: S-EPMC12076904 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature