Synergistic Enhancement of Compromised Skin Radiance: A Clinical Investigation of Prinsepia utilis Royle Polysaccharides and Nonapeptide Co-Application.

ABSTRACT:

Background

Skin radiance represents both healthy and esthetic aspects of human skin, usually influenced by a compromised barrier and the aging process. The reduction of the stratum corneum by chemical peels is a prevalent procedure employed to enhance facial radiance, but peeling is not suitable for compromised skin.

Objectives

Prinsepia utilis Royle polysaccharides (PURP) is a natural extract with repairing properties, which has been reported as a barrier repairing agent. ESETRILLQ (EQ) peptide has been recently reported as a novel antiaging bioactive peptide. This study aims to investigate the combined efficacy of these two ingredients on skin radiance enhancement.

Methods

Reconstructed human full-thickness skin models were subjected to UVA exposure, followed by tre

SUBMITTER: Qin C 

PROVIDER: S-EPMC12077750 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature