Patient Experiences of Treatment Deferral for Evaluation and Monitoring after a Trace Xpert Ultra Result.

ABSTRACT:

Background

A "trace" result from the Xpert Ultra molecular TB test indicates Mycobacterium tuberculosis DNA detection but may not always signify TB disease. Little is known about the experiences of individuals with trace results who are not immediately treated.

Methods

We enrolled Ugandan adults and adolescents with trace Xpert Ultra sputum results, plus positive and negative controls, from community-screening and clinic settings. After a comprehensive TB evaluation, participants not recommended to start treatment immediately were closely monitored with interval reassessments. Surveys captured participants' perceptions and preferences related to their uncertain TB status at baseline and during follow-up.

Results

A total of 321 people with trace sputum (PWTS), 2

SUBMITTER: Visek C 

PROVIDER: S-EPMC12077874 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature