The potential of multi- and single-cancer blood-based early detection tests in liver cancer screening.

ABSTRACT: Liver cancer is one of the most common causes of cancer deaths worldwide. Although fatal when diagnosed at an advanced stage, liver cancer has a favorable prognosis when identified at an earlier stage. Guidelines for liver cancer screening do exist, currently recommending the use of ultrasound with or without hematologic markers for early detection of liver cancer. However, studies have revealed shortcomings in the current state of liver cancer screenings such as underutilization stemming from lack of primary care education and logistical barriers for patients, suboptimal sensitivity of current screening methods, and lack of screening for lower risk individuals. A multitude of liquid biopsy tests that use circulating genomic analytes for early detection of cancers are currently under devel

SUBMITTER: Choi WJ 

PROVIDER: S-EPMC12078824 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature