Identification of lncRNAs involved in the hair follicle cycle transition of cashmere goats in response to photoperiod change.

ABSTRACT:

Background

Cashmere goats, as one of the important domesticated animal species, are known for their high-quality fiber. The growth of cashmere has seasonal variations caused by photoperiodic changes, but the molecular genetic mechanisms underlying this phenotype including the functional role of long non-coding RNAs (lncRNA) is still poorly understood.

Results

In this study, we analyzed the RNA-seq dataset of 39 Cashmere goat skin samples including all different growth stages and identified 1591 lncRNAs. These lncRNAs exhibited growth stage-specific expression patterns. Combining shortened light and hair follicle growth cycles, we found that 68% of differentially photo-responsive lncRNAs showed similar expression trends during transition phase I (early anagen to anagen phase)

SUBMITTER: Yang M 

PROVIDER: S-EPMC12080124 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature