Large-scale evidence of a general disease ('<i>d</i>') factor accounting for both mental and physical health disorders in different age groups.

ABSTRACT:

Background

It is unknown whether there is a general factor that accounts for the propensity for both physical and mental conditions in different age groups and how it is associated with lifestyle and well-being.

Methods

We analyzed health conditions data from the Millennium Cohort Study (MCS) (age = 17; N = 19,239), the National Child Development Study (NCDS) (age = 44; N = 9293), and the English Longitudinal Study of Ageing (ELSA) (age ≥ 50; N = 7585). The fit of three Confirmatory Factor models was used to select the optimal solution by Comparative Fit Index, Tucker-Lewis Index, and Root Mean Square Error of Approximation. The relationship among d factor, lifestyles, and well-being was further explored.

Results

Supporting the existence of the d factor,

SUBMITTER: Sun H 

PROVIDER: S-EPMC12080664 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature