Amplitude fluctuations of cerebrovascular oscillations and CSF movement desynchronize during NREM3 sleep.

ABSTRACT: Fluctuations in cerebral blood volume (CBV) are a dominant mechanism aiding cerebrospinal fluid (CSF) movement in the brain during wakefulness and non-rapid eye movement (NREM) sleep. However, it is unclear if the amplitudes of CBV oscillations also change in proportion to the changes in amplitude of CSF movement across specific NREM sleep states. It is also not known if the coupling strength between them varies between NREM sleep states. To investigate these relationships, we measured cerebral hemodynamics and craniad CSF movement at the fourth ventricle simultaneously during wakefulness and NREM sleep states using concurrent Electroencephalography and functional Magnetic Resonance Imaging. We found that the amplitude fluctuations of cerebral hemodynamics and CSF oscillations desynchroniz

SUBMITTER: Nair VV 

PROVIDER: S-EPMC12081394 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature