Opioid-free anaesthesia and postoperative quality of recovery in patients undergoing supratentorial tumour resection: protocol for a randomised controlled trial.

ABSTRACT:

Introduction

Opioids play a pivotal role in being capable of effectively blocking the pain and stress responses triggered by procedures such as surgery and intubation. However, it should not be overlooked that opioids have numerous side effects, such as respiratory depression, postoperative nausea and vomiting. These effects can raise intracranial pressure, posing a life-threatening risk in neurosurgical patients. Opioid-free anaesthesia can prevent or significantly reduce opioid usage. The aim of this study is to investigate the effect of opioid-free anaesthesia on the quality of recovery in patients undergoing supratentorial tumour resection in neurosurgery.

Methods and analysis

This is a single-centre, randomised controlled clinical trial. A total of 170 patients receivin

SUBMITTER: Fu Y 

PROVIDER: S-EPMC12083393 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature