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A Selenium Disulfide-Based Shampoo Is Beneficial for Dandruff Management and Rebalancing the Scalp Microbiome of Subjects of Any Hair Type.


ABSTRACT:

Introduction

Dandruff is a chronic scalp condition occurring in all hair types. Selenium disulfide (SeS2) shampoo is beneficial in dandruff and rebalances the scalp microbiome. However, data regarding subjects with curly hair are missing. This study assessed the clinical and scalp microbiome benefits of SeS2 shampoo in subjects of any hair type with moderate-to-severe dandruff.

Methods

A 6-week study in adult subjects of any De La Mettrie hair type (I-VIII) assessed total dandruff, SD severity score (SSSD), erythema, hair greasiness, quality of life, discomfort, local tolerance, perceived benefit, acceptability, cosmeticity, and changes in the scalp microbiota. SeS2 shampoo was applied twice every week.

Results

Overall, 93 subjects of

SUBMITTER: Reygagne PE 

PROVIDER: S-EPMC12084028 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature