Common bean pan-genome reveals abundant variation patterns and relationships of stress response genes and pathways.

ABSTRACT: Long-term geographical isolation and the different directions of domestication can cause a large number of genome variations. Population genetic analysis based on a single reference genome cannot capture all the variation information. Pan-genome construction is an effective way to overcome this problem. Resequencing data from 683 common bean landraces and breeding lines provided a pan-genome construction data resource. For the first time, for common bean pan-genome construction, 305 Mb non-reference contigs and 10,452 novel genes were identified. Among these new genes, 373 resistance gene analogs containing 372 variable genes were identified and used to narrow down the candidate genes in Pseudomonas syringae pv. phaseolicola resistance quantitative trait locus interval of the common bean.

SUBMITTER: Wang X 

PROVIDER: S-EPMC12084947 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature