Liver metabolomic profiles of sea lamprey (Petromyzon marinus) are influenced by sex and maturation stages.

ABSTRACT:

Introduction

Sea lamprey (Petromyzon marinus) is a unique vertebrate model to examine how liver metabolomes support different reproductive functions. Juvenile sea lamprey prey on other fish species by attaching to their body and feeding on their blood and body fluids. Once reaching adulthood, they cease feeding, migrate to spawning streams and begin their final sexual maturation. During these processes, the male livers produce large quantities of bile acid pheromone precursors to be modified and released via gills, whereas the female livers synthesize vast amounts of vitellogenin (yolk lipophosphoprotein) to be transported to the ovary.

Objective

We aim to test the hypothesis that the liver metabolic pathways exhibit dramatic changes during sexual maturation of sea lampreys

SUBMITTER: Tamrakar S 

PROVIDER: S-EPMC12085385 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature