Myopia control using a modified optical defocus soft contact lens in schoolchildren-A 12-month randomised double masked control trial.

ABSTRACT:

Purpose

Defocus Incorporated Soft Contact (DISC) lenses with +2.50 D myopic defocus reduced myopia progression by 25% in a previous randomised clinical trial (RCT). The current study aimed to evaluate if a stronger myopic defocus, +3.50 D with variable myopic defocus (DISC3.5plus), could slow myopia progression compared with single vision (SV) soft contact lenses in a 12-month RCT.

Methods

Conducted from December 2018 to January 2021, the current RCT randomly assigned myopic children to wear DISC3.5plus (n = 87) or SV (n = 80) lenses. Myopia progression and axial elongation were compared between the two groups. Analyses were performed for both enrolled and completed participants.

Results

For all enrolled participants, the DISC3.5plus group had significantly less myopi

SUBMITTER: Zhang H 

PROVIDER: S-EPMC12087850 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature