Anthropometric and metabolic differences and distribution of ABCG2 rs2231142 variant between lowland and highland Papuans in West Papua, Indonesia.

ABSTRACT:

Background

Papuan people inhabiting the island of New Guinea are the most ancient population living outside Africa, having resided in the region for at least 50,000 years. The arrival of Austronesian speakers and other group from mainland Asia around 3000 years or so created a peculiar genetic mixture, particularly in lowland/coastal areas. We investigated the anthropometric and blood chemical differences alongside the population structure of the ABCG2 rs2231142 genetic variant of West Papuans from lowland/coastal and highland areas to understand metabolic risk differences between these two populations.

Results

We studied West Papuan students from lowland/coastal areas (n = 78, 45 males, 33 females) and from highland areas (n = 65, 40 males, 25 females). We found the followi

SUBMITTER: Karwur FF 

PROVIDER: S-EPMC12090604 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature