Influence of internal limiting membrane peeling during idiopathic epiretinal membrane removal: a randomized controlled trial.

ABSTRACT: In epiretinal membrane (ERM) surgery, the influence of internal limiting membrane (ILM) integrity after ERM removal is underexplored. This study investigated outcomes of idiopathic ERM surgery based on ILM condition following ERM removal and intentional peeling of residual ILM. In this prospective, randomized clinical trial, 102 patients underwent vitrectomy for idiopathic ERM. After ERM removal, ILM status was evaluated using indocyanine green staining. Patients with mostly removed ILM were allocated to group 1 (involuntary peeling), whereas those with partially removed or intact ILM were randomized 1:1 to active peeling (group 2) or non-peeling of residual ILM (group 3). Recurrence of ERM during 12-month follow-up occurred only in group 3 (36.1%), particularly when residual ILM involved

SUBMITTER: Kim BH 

PROVIDER: S-EPMC12092785 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature