Comparing hemodialysis and hemodiafiltration performance with and without hemoadsorption.

ABSTRACT:

Background

New cartridges have been developed using the latest resins for hemoadsorption (HA). When used alongside dialyzers, these cartridges may enhance the removal of certain uremic toxins achieved with classical diffusion and convection. This study aimed to assess the elimination of a wide range of molecular weight solutes, including protein-bound uremic toxins, in hemodialysis (HD) and postdilution hemodiafiltration (HDF) treatments.

Methods

A prospective study was conducted involving 20 patients who underwent six dialysis sessions with routine treatment parameters maintenance, while only the dialysis modality was modified. The modalities included low-flux HD (LFHD), LFHD-HA, high-flux HD (HFHD), HFHD-HA, HDF and HDF-HA.

Results

Urea and creatinine reduction rati

SUBMITTER: Maduell F 

PROVIDER: S-EPMC12093098 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature