Evaluation of two commercial IBR marker vaccines against <i>Bubaline alphaherpesvirus 1</i> in water buffalo (<i>Bubalus bubalis</i>).

ABSTRACT: The present study aimed to evaluate two commercial infectious bovine rhinotracheitis (IBR) marker vaccines against Bubaline alphaherpesvirus 1 (BuAHV-1) in water buffalo (Bubalus bubalis). Thirteen water buffaloes seronegative to Bovine alphaherpesvirus 1 (BoAHV-1) and BuAHV-1 were selected and divided into three groups (VAX-1, VAX-2, CNT). VAX-1 received an IBR marker (gE-/tk-) live vaccine; VAX-2 received an IBR marker (gE-) inactivated vaccine; CNT represented the controls. Two injections of 2 mL each were administered 21 days apart. On 55 post-vaccination days (PVDs), all animals were challenged infected with wild-type BuAHV-1. Nasal swabs and serum samples were collected at different experimental times and were used for virological, serological and immunological investig

SUBMITTER: Cappelli G 

PROVIDER: S-EPMC12094042 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature