Predicting whole-brain neural dynamics from prefrontal cortex functional near-infrared spectroscopy signal during movie-watching.

ABSTRACT: Functional near-infrared spectroscopy (fNIRS) offers a portable, cost-effective alternative to functional magnetic resonance imaging (fMRI) for noninvasively measuring neural activity. However, fNIRS measurements are limited to cortical regions near the scalp, missing important medial and deeper brain areas. We introduce a predictive model that maps prefrontal fNIRS signals to whole-brain fMRI activity during movie-watching. By aligning neural responses to a common audiovisual stimulus, our approach leverages shared dynamics across imaging modalities to map fNIRS signals to broader neural activity patterns. We scanned participants with fNIRS and utilized a publicly available fMRI dataset of participants watching the same TV episode. The model was trained on the first half of the episode an

SUBMITTER: Gao S 

PROVIDER: S-EPMC12094161 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature