Heterogeneity of Treatment Outcomes Across Therapists and Sites in a Randomized Multicentre Psychotherapy Trial.

ABSTRACT:

Objective

Establishing robust evidence for psychotherapeutic treatment efficacy is crucial in evidence-based medicine for mental disorders. Randomized controlled trials (RCTs) are key to minimizing biases such as selection effects and baseline imbalances between study groups. However, another challenge to robust evidence in psychotherapy research is heterogeneity in treatment outcomes due to therapists and clinical sites. While this has been frequently observed in naturalistic settings, therapist- and site-related heterogeneity in treatment outcomes has been understudied in RCTs.

Method

The present study addresses this gap in a secondary data analysis, examining how therapists and clinical sites differ in treatment outcomes and differential/average treatment effect (i.e., ou

SUBMITTER: Petter J 

PROVIDER: S-EPMC12095096 | biostudies-literature | 2025 May-Jun

REPOSITORIES: biostudies-literature