Population attributable fraction of total stroke associated with modifiable risk factors in the United States.

ABSTRACT: Stroke is a leading cause of death in the United States across all race/ethnicity and sex groups, though disparities exist. We investigated the potential for primary prevention of total first stroke for Americans aged 20 years or older, stratified by sex and race/ethnicity. Specifically, we calculated population attributable fractions (PAFs) of first stroke for 7 potentially modifiable risk factors: smoking, physical inactivity, poor diet, obesity, hypertension, diabetes, and atrial fibrillation. Population attributable fractions are a function of (1) the relative risk of first stroke for people with the exposure and (2) the prevalence of the risk factor in the population. Relative risks came from recent meta-analyses, and sex- and race/ethnicity-specific prevalence estimates came from the

SUBMITTER: Lee M 

PROVIDER: S-EPMC12096310 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature