Vasopressin Is Not Associated With Severe Kidney Injury in Liver Transplantation: A Propensity Score-adjusted Analysis.

ABSTRACT:

Background

Hypotension during liver transplantation often requires vasopressor therapy. Acute kidney injury is a common complication after liver transplantation. Vasopressin acts as a portal flow modulator, may increase the glomerular filtration rate, and reduce the dose of catecholamines required. We hypothesized that intraoperative vasopressin use could be associated with reduced postoperative acute kidney injury.

Methods

This single-center retrospective cohort study included 1120 adult liver transplant recipients between June 2012 and November 2022. We assessed the association between intraoperative vasopressin use and postoperative severe acute kidney injury by using a propensity score-adjusted multivariable regression model.

Results

The incidence of severe postop

SUBMITTER: Antonucci E 

PROVIDER: S-EPMC12097770 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature