Decoding auditory working memory content from EEG responses to auditory-cortical TMS.

ABSTRACT: Working memory (WM), short term maintenance of information for goal directed behavior, is essential to human cognition. Identifying the neural mechanisms supporting WM is a focal point of neuroscientific research. One prominent theory hypothesizes that WM content is carried in "activity-silent" brain states involving short-term synaptic changes. Information carried in such brain states could be decodable from content-specific changes in responses to unrelated "impulse stimuli". Here, we used single-pulse transcranial magnetic stimulation (spTMS) as the impulse stimulus and then decoded content maintained in WM from EEG using multivariate pattern analysis (MVPA) with robust non-parametric permutation testing. The decoding accuracy of WM content significantly enhanced after spTMS was deliver

SUBMITTER: Uluc I 

PROVIDER: S-EPMC12097927 | biostudies-literature | 2025 May-Jun

REPOSITORIES: biostudies-literature