Biosynthesis of bimetallic silver-copper oxide nanoparticles using endophytic <i>Clonostachys rosea</i> ZMS36 and their biomedical applications.

ABSTRACT: Bimetallic nanoparticles (BMNPs) have garnered significant interest owing to their exceptional physicochemical properties. However, there have been few reports of the biosynthesis of BMNPs using endophytic fungi from medicinal plants. The objectives of this study were to isolate endophytic fungi from medicinal plant Anemarrhena asphodeloides to synthesize bimetallic Ag-CuO nanoparticles (Ag-CuO NPs), characterize the biosynthesized Ag-CuO NPs and assess their bioactivity and biosafety. The endophytic fungus ZMS36 capable of biosynthesizing Ag-CuO NPs was isolated from medicinal plant A. asphodeloides and identified as Clonostachys rosea. The Ag-CuO NPs were biosynthesized using endophytic C. rosea ZMS36 and characterized by UV-visible, SEM, TEM, EDS, XRD, and FT

SUBMITTER: Chen Z 

PROVIDER: S-EPMC12098627 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature