Frequency and determinants of use of immunosuppressants in the Australian Scleroderma Cohort Study.

ABSTRACT:

Objectives

To assess the frequency and determinants of immunosuppressant medication use in systemic sclerosis and changes in prescribing patterns over time.

Methods

The Australian Scleroderma Cohort Study participants meeting the American College of Rheumatology/European Alliance of Associations for Rheumatology criteria for systemic sclerosis with recorded treatment data were included. The Chi-square, two-sample t-tests or Wilcoxon rank-sum tests were used for between-group comparison as appropriate. Multivariable logistic regression models were used to establish the determinants of the use of immunosuppressants.

Results

Of 2019 participants, 60% received immunosuppressants, including 81% of those with diffuse systemic sclerosis and 52% of those with limited s

SUBMITTER: Fairley JL 

PROVIDER: S-EPMC12102085 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature