Phytochemical, biological, DFT, and molecular docking evaluation of Euphorbia paralias.

ABSTRACT: This study aimed to bridge the knowledge gap in the unclear previous studies of the molecular processes that cause the biological activities of Euphorbia paralias by integrating phytochemical analysis with quantum chemical calculations and molecular docking investigations, providing unprecedented insights into the therapeutic potential of its chemical constituents. Seven important flavonoids were isolated and identified using spectroscopic techniques, and 34 and 13 additional compounds were identified via GC/MS analysis of the hexane and chloroform fractions, respectively. The crude methanol extract, some fractions, and isolated compounds were screened for antimicrobial activity against Gram-positive and Gram-negative bacteria. Among the tested constituents, β-sitosterol-3-O-β-D-glucoside

SUBMITTER: Kamel AI 

PROVIDER: S-EPMC12102368 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature