A hemicyanine-based dual-responsive fluorescent sensor for the detection of lithium and cyanide ions: application in living cells.

ABSTRACT: A hemicyanine-based colorimetric and fluorometric sensor, 2-(2-(2,3,5,6,8,9-hexahydrobenzo[b][1,4,7,10]tetraoxacyclododecin-12-yl)vinyl)-3,3-dimethyl-1-propyl-3H-indol-1-ium iodide (MH-5), was developed and synthesized to detect Li⁺ and CN^- ions in DMSO-PBS buffer solution (10 mM, pH 7.25, v/v 1:9). MH-5 displayed a rapid and highly selective colorimetric response to both Li⁺ and CN^-, indicated by a distinct color change from pink to pale pink in the presence of Li⁺ and to colorless upon CN^- detection, without interference from other cations or anions. The interaction mechanisms of MH-5 with Li⁺ and CN^- ions were investigated using various analytical techniques, including ¹H NMR, ESI-MS, FT-I

SUBMITTER: Aydin Z 

PROVIDER: S-EPMC12103329 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature