Genomic profiling of <i>Streptococcus agalactiae</i> (Group B <i>Streptococcus</i>) isolates from pregnant women in northeastern Mexico: clonal complexes, virulence factors, and antibiotic resistance.

ABSTRACT:

Background

Streptococcus agalactiae (Group B Streptococcus, GBS) is an important pathogen associated with neonatal sepsis, pneumonia, and meningitis, which can be transmitted from colonized pregnant women to their newborns. This study aimed to determine the prevalence and characterize the genomic features of S. agalactiae isolates from pregnant women attending a referral hospital in Northeastern Mexico.

Methods

Vaginal-rectal swabs were collected from pregnant women during routine prenatal care between April 2017 and March 2020. Whole-genome sequencing was conducted to determine sequence type (ST), clonal complex (CC), capsular polysaccharide (Cps) genotype, virulence factors, and antibiotic resistance genes through comparative genome analysis.

Result

SUBMITTER: Vazquez-Guillen JM 

PROVIDER: S-EPMC12103846 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature