Oral supplement in healthy older adults to support physical fitness and mental wellbeing.

ABSTRACT:

Introduction

Cucumbers have been anecdotally credited with anti-inflammatory properties. IdoBR1 [(2R,3R,4R,5S)-3,4,5-trihydroxypiperidine-2-carboxylic acid], an iminosugar amino acid isolated from the fruits of certain cucumbers (Cucumis sativus, Cucurbitaceae), has been demonstrated to possess anti-inflammatory activity. Q-actin™ is a quality-controlled cucumber extract containing measured idoBR1, which has shown promising results in the treatment of osteoarthritis through oral administration.

Methods

A healthy middle-aged and older adult population was recruited and randomized to receive either Q-actin™ (2 × gummies containing 10 mg Q-actin™ daily) or matched placebo gummies for 12 weeks. Physical strength and finger dexterity were assess

SUBMITTER: Lloyd AJ 

PROVIDER: S-EPMC12104766 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature