Leukopenia and thrombocytopenia in dengue patients: a cross-sectional study from a tertiary hospitals in Koshi Province, Nepal.

ABSTRACT:

Introduction

Dengue fever remains a public health challenge in Nepal, with hematological abnormalities like leukopenia and thrombocytopenia often observed. However, their prevalence and clinical significance outside the Kathmandu Valley remain poorly characterized. This study examines these markers in Koshi Province, a region prone to recurrent outbreaks but with limited data, to enhance regional understanding and early severity detection.

Methods

A cross-sectional study was conducted across four tertiary hospitals in Sunsari district, Koshi province of Nepal during the 2022 dengue outbreak. A convenience sample of 325 laboratory-confirmed dengue patients (NS1 antigen/IgM/IgG positivity) was enrolled. Data on demographics, clinical features, leukocytes count, and platelet co

SUBMITTER: Gupta BP 

PROVIDER: S-EPMC12105263 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature