The extent of Skeletal muscle wasting in prolonged critical illness and its association with survival: insights from a retrospective single-center study.

ABSTRACT:

Objective

Muscle wasting in critically ill patients, particularly those with prolonged hospitalization, poses a significant challenge to recovery and long-term outcomes. The aim of this study was to characterize long-term muscle wasting trajectories in ICU patients with acute respiratory distress syndrome (ARDS) due to COVID-19 and acute pancreatitis (AP), to evaluate correlations between muscle wasting and patient outcomes, and to identify clinically feasible thresholds that have the potential to enhance patient care strategies.

Materials and methods

A collective of 154 ICU patients (100 AP and 54 COVID-19 ARDS) with a minimum ICU stay of 10 days and at least three abdominal CT scans were retrospectively analyzed. AI-driven segmentation of CT scans quantified changes in pso

SUBMITTER: Kolck J 

PROVIDER: S-EPMC12105279 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature