Cognitive functions in schizophrenia: the interplay between blood viscosity, serum osmolarity, and symptom severity.

ABSTRACT:

Objective

Cognitive impairments-especially in executive function and attention-are core features of schizophrenia and major barriers to functional recovery. Although systemic physiological factors such as blood viscosity and serum osmolarity have been implicated in schizophrenia, their association with cognitive deficits remains largely unexplored. This study aimed to investigate these relationships in male patients with schizophrenia in remission.

Methods

A total of 247 male patients diagnosed with schizophrenia in remission were recruited. Cognitive performance was assessed using the Frontal Assessment Battery (FAB), Stroop Test, and Trail Making Test (TMT). Hemorheological parameters, including whole blood viscosity (WBV) at low and high shear rates (LSR and HSR), and ser

SUBMITTER: Ozonder Unal I 

PROVIDER: S-EPMC12105296 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature