The effects of the mediterranean diet supplemented with olive oils on pro-inflammatory biomarkers and soluble adhesion molecules: a systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Background

Inflammation plays a pivotal role in Cardiovascular disease (CVD) which are a major global health burden. The oil-supplemented Mediterranean diet (MED) is associated with anti-inflammatory effects. The current study evaluates the impact of an olive oils-supplemented MED on pro-inflammatory biomarkers and soluble adhesion molecules.

Methods

Regarding PRISMA guideline, this study was conducted and PubMed, Scopus, Web of Science (ISI), Embase, CINAHL databases as well as Google Scholar and Cochrane Library were systematically searched till June 2024.

Results

15 clinical trials (20 arms) comprising 2477 adults aged 23-80 years were included in the systematic review and 9 of them were entered in the meta-analysis. We revealed that following an enriched MED with

SUBMITTER: Tehrani SD 

PROVIDER: S-EPMC12105412 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature