Blood Pressure Trajectories During Young Adulthood and Cardiovascular Events in Later Life.

ABSTRACT:

Background

Studying the association between blood pressure (BP) trajectories during young adulthood and subsequent cardiovascular disease (CVD) risk can provide insights into how long-term BP patterns in early-life influence the development of CVD later in life.

Methods

We pooled data from 2 US cohorts (Coronary Artery Risk Development in Young Adults, Framingham Heart Study). We used latent growth curve models to identify distinct BP trajectory groups between ages 18 and 39 years. We then used Cox proportional hazards models to assess the associations between BP trajectories and CVD events (composite of coronary heart disease [CHD], stroke, and heart failure [HF]) after age 40 years.

Results

We included 6,579 participants and identified 4 distinct systolic BP (SBP) t

SUBMITTER: Xia M 

PROVIDER: S-EPMC12106888 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature