Continuous glucose monitor overestimates glycemia, with the magnitude of bias varying by postprandial test and individual - a randomized crossover trial.

ABSTRACT:

Background

Continuous glucose monitors (CGM) are used to characterize postprandial glycemia, yet no study has directly tested how different test foods/beverages alter CGM accuracy.

Objectives

Assess glycemic responses to test foods/drinks using CGM compared with capillary sampling (criterion).

Methods

Fifteen healthy females (n = 9) and males (n = 6) completed 7 laboratory visits in a randomized crossover design with ≥48 h washout between visits. During each visit, participants consumed an oral carbohydrate challenge comprising either 50 g glucose or equivalent 50 g carbohydrate as whole fruits, 50 g carbohydrate as blended fruit, 50 g carbohydrate as commercially available fruit smoothie, 50 g carbohydrate as commercially available fruit smoothie ingested over 30 ± 4

SUBMITTER: Hutchins KM 

PROVIDER: S-EPMC12107490 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature