Investigating dose-dependent effects of chemical compounds targeting rumen fermentation pathways using an in-vitro rumen fermentation system.

ABSTRACT:

Background

Ruminal fermentation leads to the formation of methane (CH₄) as a byproduct, which is one of the major greenhouse gases. Despite extensive research efforts involving the use of various anti-methanogenic and hydrogen sink compounds, the current understanding of the dose-response effects of these compounds on the rumen microbiome and fermentation profile is limited. In this study, potential methanogenesis inhibitors or electron acceptors were evaluated for their effects on methane production, fermentation, and prokaryotic community composition. Dose-response effects of sodium 2-bromoethanesulfonate (BES: 0, 2.5, 5, 10 mmol/L), p-hydrocinnamic acid (HoC: 0, 5, 10 mmol/L), and sodium fumarate dibasic (DFS: 0, 5, 10, 20 mmol/L) on dry matter degradation, total gas

SUBMITTER: Dhakal R 

PROVIDER: S-EPMC12107880 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature